PRADA: Portable Reusable Accurate Diagnostics with nanostar Antennas for multiplexed biomarker screening

Multiplexed tissue biomarker imaging.

Description of the technology The detection of structural and functional proteins in cells within the tumor microenvironment in tissue samples is achieved by immunolabeling with specific antibodies. These target proteins are visualized with the subsequent application of either an enzymatic reaction that induces chromogen precipitation at the site of antibody-antigen binding (immunoenzyme method...

Novel microfluidic technologies for portable diagnostics systems

Novel microfluidic technologies being developed for portable diagnostic systems have potential for use in TB serodiagnosis or as platforms for cell and biomolecular assays. Using microfluidics, with its miniaturized channels and reservoirs for portable devices, offers many advantages, including: high surface-to-volume ratio; a low Reynolds number; increased speed of reaction; reduced cost of re...

General Guide for Accurate Weighing with Portable Wheel Load Scales

Portable and accurate sampling profiling for Java

This article presents a novel framework for the sampling-based profiling of Java programs, which relies on program transformation techniques. We exploit bytecode instruction counting to regularly activate a user-defined profiling agent, which processes the current call stack. This approach has several advantages, such as making the instrumentation entirely portable, generating reproducible prof...

On device abstractions for portable, reusable robot code

We seek to make robot programming more efficient by developing a standard abstract interface for robot hardware, based on familiar techniques from operating systems and network engineering. This paper describes the application of three well known abstractions, the character device model, the interface/driver model, and the client/server model to this purpose. These abstractions underlie Player/...